The second European IGSTK user group meeting was held on June 22, 2010, in Geneva, Switzerland. The meeting was held the evening before the beginning of the Computer Aided Radiology and Surgery (CARS) conference. There were about 15 attendees representing different institutions worldwide and the seven speakers discussed their work with IGSTK and related software. The applications presented included robotically assisted neurosurgery, cone-beam CT guided head and neck surgery, and liver surgery. The schedule and presentations can be seen on the IGSTK Wiki.